Product Specifications:
• Molecular Formula: C194H312N54O59S2
• Molecular Weight: 4409.01 g/mol
• CAS Number: 1415456-99-3
• Total Volume: 5mg total active chemical weight per vial
• Structural Feature: Acylated peptide containing a C3-C8 disulfide bridge
• Physical Profile: Homogeneous, white lyophilized cake
Product Overview:
Cagrilintide (commonly denoted in research environments as Cagril) is an engineered, long-acting analogue of the human pancreatic peptide hormone amylin. In metabolic and endocrinology research settings, this synthetic peptide is heavily investigated for its distinct dual agonist mechanism of action, selectively binding to both non-selective amylin receptors (AMYR) and calcitonin G-protein coupled receptors (CTR).
Investigational Vectors:
1. Dual Pathway Appetite Regulation: Researchers study how secondary amylin receptor binding path modifications alter downstream signal transduction in the caudal hindbrain compared to traditional single-pathway GLP-1 analogues.
2. Gastric Kinetic Alterations: In vitro and animal models evaluate the compound’s impact on suppressing postprandial glucagon secretion and regulating gastric emptying rates.
3. Incretin Synergy Dynamics: Widely utilized in co-administration models alongside GLP-1 receptor agonists (such as Semaglutide) to observe cumulative cellular metabolic shifts and receptor cross-talk.





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