5-Amino-1MQ 50mg (Research Grade)

Product Specifications:
• Chemical Name: 1-Methylquinoline-5-amine
• Molecular Formula: C10H11N2+
• Molecular Weight: 159.21 g/mol
• CAS Number: 42464-96-0
• Total Active Mass: 50mg per vial
• Physical Profile: Lyophilized powder / crystalline solid

Product Overview:
5-Amino-1MQ is a cell-permeable, selective small molecule inhibitor of Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide (NAM). Unlike larger peptide chains, 5-Amino-1MQ acts as a direct enzymatic block within targeted cellular structures.

Investigational Vectors:
1. NNMT Pathway Inhibition: Researchers study the compound’s capability to suppress NNMT activity, leading to a downstream increase in intracellular NAD+ levels and direct up-regulation of SIRT1 signaling.
2. Adipocyte Metabolism Kinetics: In vitro and animal models evaluate the compound’s impact on energy expenditure, lipid storage variations, and intracellular remodeling pathways in fat cell lines.
3. Skeletal Muscle Cell Vitality: Investigated for its regulatory role in cellular senescence, muscle stem cell proliferation, and functional recovery mechanisms during metabolic stress mapping.

Open COA