Kisspeptin-10 10mg (Research Grade)

Product Specifications:
• Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
• Molecular Formula: C63H78N18O13
• Molecular Weight: 1302.43 g/mol
• CAS Number: 423744-53-4
• Total Active Mass: 10mg per vial
• Physical Profile: Homogeneous, white lyophilized cake

Product Overview:
Kisspeptin-10 is a synthetic decapeptide representing the minimum structurally active sequence derived from the full-length human KISS1 gene product. In neuroendocrinology and reproductive biology research settings, this fragment functions as a highly potent agonist of the G-protein coupled receptor KISS1R (formerly known as GPR54). It serves as a foundational upstream gateway chemical used to observe the triggers of pulsatile endocrine secretions.

Investigational Vectors:
1. GnRH Secretory Cascade Modulation: Researchers study the peptide’s capability to stimulate hypothalamic Kisspeptin receptors, evaluating downstream calcium mobilization that triggers pulsatile Gonadotropin-Releasing Hormone (GnRH) release.
2. Gonadotropin Axis Amplification: In vitro and animal models evaluate how Kisspeptin-10 administration indirectly upregulates serum Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) levels without direct pituitary binding.
3. Cellular Invasiveness and Metastasis Dynamics: Investigated for its secondary regulatory behavior in oncology models, specifically tracking how KISS1R binding pathways suppress cellular motility and tissue migration mechanics.

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