Product Specifications:
• Chemical Name: Glycyl-L-histidyl-L-lysine copper complex
• Molecular Formula: C14H22CuN6O4
• Molecular Weight: 401.91 g/mol
• CAS Number: 89030-95-5
• Total Active Mass: 50mg per vial
• Format: Lyophilized powder / crystalline matrix
• Visual Profile: Deep, vibrant blue hue (characteristic of divalent copper coordination)
Product Overview:
GHK-Cu is a synthetically manufactured tripeptide complexed with divalent copper ions (Copper II). In structural biology and cellular matrix research, this compound serves as a specialized carrier system studied for its ability to regulate intracellular copper homeostasis without inducing localized heavy metal toxicity or free radical accumulation. It is a foundational tool for evaluating tissue remodeling and gene expression patterns in vitro.
Investigational Vectors:
1. Extracellular Matrix Upregulation: Researchers study the compound’s capability to modulate fibroblasts, monitoring downstream transcription changes in collagen, elastin, and decorin synthesis pathways.
2. Anti-Inflammatory Gene Expression: In vitro models evaluate GHK-Cu for its impact on suppressing pro-inflammatory cytokines (such as IL-1 and TNF-alpha) and upregulating antioxidant enzyme expressions like superoxide dismutase.
3. Stem Cell Remodeling & Proliferation: Investigated for its regulatory role in tracking the survival kinetics of basal keratinocytes and evaluating cell transposition during mechanical tissue stress simulation.




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