GHRP-2 5mg (Growth Hormone Releasing Peptide-2)

Product Specifications:
• Sequence: D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
• Molecular Formula: C45H55N9O6
• Molecular Weight: 817.99 g/mol
• CAS Number: 158861-67-7
• Total Active Mass: 5mg per vial
• Physical Profile: Homogeneous, white lyophilized cake

Product Overview:
GHRP-2 (Growth Hormone Releasing Peptide-2, also known as Pralmorelin) is a synthetic, second-generation hexapeptide that functions as a potent agonist of the growth hormone secretagogue receptor (GHS-R). It mimics the binding dynamics of endogenous ghrelin. In endocrine and metabolic research models, GHRP-2 is utilized to investigate downstream cellular signaling cascades that regulate somatotroph activity and systemic hormone release kinetics without relying on native GHRH pathways.

Investigational Vectors:
1. Pituitary Somatotroph Activation: Researchers study the compound’s binding affinity to central GHS-R receptors to map cyclic adenosine monophosphate (cAMP) accumulation and intracellular calcium influx.
2. Dual Secretagogue Synergy: In vitro and animal models evaluate how GHRP-2 co-administration with Growth Hormone-Releasing Hormone (GHRH) alters the baseline pulsatile release envelope of growth hormone.
3. Orexigenic Receptor Mapping: Investigated for its regulatory role in the hypothalamus, specifically evaluating how it interacts with ghrelin networks to trigger secondary appetite and gastric kinetic pathways.

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