Product Specifications:
• Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
• Molecular Formula: C78H123N23O23S2
• Molecular Weight: 1815.1 g/mol
• CAS Number: 221231-10-3
• Total Active Mass: 5mg per vial
• Physical Profile: Homogeneous, white lyophilized cake
Product Overview:
HGH Fragment 176-191 is a synthetic peptide that isolates the specific carboxyl-terminus region of the human growth hormone molecule (amino acids 176 through 191). In cellular physiology and endocrinology research settings, this fragment is utilized to evaluate targeted lipolytic mechanics. By isolating this precise terminal sequence, researchers can observe localized lipid degradation pathways without triggering the secondary somatogenic, IGF-1 promoting, or insulin-sensitizing pathways native to full-length recombinant human growth hormone.
Investigational Vectors:
1. Targeted Lipolysis Transduction: Researchers study the peptide’s capability to induce fat breakdown signaling within isolated adipocyte lines by tracking beta-3 adrenergic receptor pathways.
2. Suppression of Lipogenesis: In vitro and animal models analyze how this truncated sequence restricts the entry of unesterified fatty acids into targeted fat matrices, reducing structural lipid storage.
3. Glycemic Variance Mitigation: Investigated to verify its metabolic isolation profile, specifically examining its lack of affinity for growth hormone receptors that cause serum glucose fluctuations and insulin resistance.
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